Method for Predicting Outcomes of Arterial Ischemia Surgical Treatment

Roman Komarov ¹, Andrey Dzyundzya ¹, Oleg Vinogradov ¹, Philipp Kopylov  ¹, Garik Frangulyan ¹, Yuri Vassilevski ², Sergey Simakov ³

¹ I.M. Sechenov First Moscow State Medical University, Moscow, Russia; ² The Institute of Numerical Mathematics of the Russian Academy of Sciences , Moscow, Russia; ³ Moscow Institute of Physics and Technology (State University), Moscow, Russia;

Date, time and location: 2018.05.26 13:30, Exhibition area, 1st Floor. Zone – B

Abstract

Objective: To evaluate the role of mathematical modeling in the diagnosis and treatment of the aorta and arteries atherosclerotic lesions in the lower extremities.

Matherials and methods: At the present time, there are several basic methods for visualizing arterial lesions and selecting treatment tactics: ultrasonic triplex scanning, angiography and computer angiography. However, these methods alone do not make it possible to predict the outcome of the reconstructive intervention. In the department of cardiosurgery, 12 patients with significant lesion of the aorto-femoral and femoropoplite segments were treated. Men 10 (83.3%), women 2 (16.7%). All patients underwent a one-stage multilevel restoration of blood flow in affected segments on the basis of preoperative examination data by standard methods and using mathematical modeling of blood flow.

Results: Using local models of three-dimensional currents, the blood streams in sections of the affected arterial segments and their branches were examined in detail, including a detailed analysis of the flow in the bifurcation region of the main arteries and their branches. One-dimensional network models allow analyzing blood flow through the arteries in a complex manner throughout the arterial network before reconstructive treatment and virtually simulating the outcome of surgical treatment.

Conclusion: Mathematical models and modern technologies allow analyzing the blood flow in the affected arteries of the aorto-femoral and femoral-popliteal segments, making a virtual assessment and modeling the outcomes of the arterial reconstructions of the affected segments, which makes it possible to work out the optimal tactics and scope of surgical intervention.