The Impact of Coronary Heart Disease on Energy Efficiency of the Epicardium of the Left Ventricle

Olga Bockeria, Tatyana Le, Anna Satyukova, Marina Mironenko, Lyudmila Glushko, Vladimir Schwartz

National medical research center for cartdiovascular surgery named after A N Bakulev, Moscow, Russia

Date, time and location: 2018.05.26 17:00, Exhibition area, 1st Floor. Zone – A

Abstract

Objective. The aim of this study was to perform a quantitative analysis of energy efficiency of the epicardium in patients with coronary heart disease (CHD).

Methods. There have been examined and enrolled in the study 150 patients. They were divided into 3 groups: patients with right coronary artery (RCA) lesions without MI (n = 50); patients with left anterior descending artery (LAD) lesions without MI (n = 50); patients with LAD lesions and MI (n = 50). The following parameters have been evaluated: amplitude, speed of longitudinal deformation, speed of rotation, the radial strain deformation. The energy efficiency index has been calculated to compare the differences of the LV areas movement. The Shapiro-Wilk test, Kruskal-Wallis test were performed «Statistica 10.0» program.

Results. A comparative analysis of variance (Kruskal-Wallis test) showed no statistically significant differences between the areas of energy efficiency of epicardium in groups of patients without MI (P>0,016). Statistically significant differences was observed in the groups of patients with LAD lesions without MI and with LAD lesions with MI: at basal level between anterior and lateral walls of the left ventricle (P<0,016), the anterior and posterior walls (P<0,016); at the apex zone between the anterior and lateral walls of LV (P<0,016), the anterior and posterior walls (P<0,016), on the basal and middle levels on the anterior, lateral and posterior walls of the LV.

Conclusions. The highest energy efficient level was detected on the apex of the anterior wall in patients with right coronary artery lesions without MI and in the basal level of the lateral wall of LV in patients with LAD lesions without MI.